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位置: 首页> 品牌> Sigma-Aldrich> Anti-Fibrillin (Pan) Antibody, clone 689

Anti-Fibrillin (Pan) Antibody, clone 689

品牌
Sigma-Aldrich
货号
MAB2641
规格纯度
clone 689, from mouse
价格
6022.61 *本价格含增值税费
促销
服务
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  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Fibrillin (Pan) Antibody, clone 689
EGF-containing fibulin-like extracellular matrix protein 1, Fibrillin-like protein, Extracellular protein S1-5
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Fibrillins are glycosolated and disulfide-rich components of the extracellular matrix belonging to the Fibrillin-LTBP protein family. They serve an important function in both nonelastic and elastic tissues such as eye, bone and blood vessels. The functional units of Fibrillin are known as microfibrils, multiprotein assemblies, which act as structural scaffolding for the limiting of the tissue elasticity, structural integrity of different organ systems, the assembly of elastic fibers, and regulation of BMP growth factor signaling. There are three known isoforms; Fibrillin 1, Fibrillin 2, and Fibrillin 3. Fibrillin 3 is the most recently described member of the Fibrillin family, with highest expression in the brain. Alterations in the microfibril assembly often occur in patients with fibrillinopathies such as; Congenital Contractual Arachnodactyly (CCA) which results in disruption of Fibrillin 2, and Marfan’s syndrome resulting from Fibrillin 1 mutation.

特异性

The antibody recognizes isoforms 1, 2, and 3 of fibrillin.

免疫原

Recombinant protein corresponding to human Fibrillin 3.

应用

ELISA Analysis: This antibody has been used by an independent laboratory in ELISA (Corson, 2003).
Anti-Fibrillin (Pan) Antibody, clone 689 detects level of Fibrillin (Pan) & has been published & validated for use in IH, ELISA.

质量

Evaluated by Immunohistochemistry in fresh frozen mouse skin tissue.

Immunohistochemistry Analysis: 1:200 dilution of the antibody detected Fibrillin (Pan) in fresh frozen mouse skin tissue.

目标描述

~ 350 kDa calculated

外形

Protein G Purified
Format: Purified

分析说明

Control
Mouse skin tissue

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 689, monoclonal
species reactivity mouse
species reactivity (predicted by homology) human (based on 100% sequence homology), chicken (based on 100% sequence homology)
technique(s) ELISA: suitable
immunohistochemistry: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_115823
UniProt登记号 Q75N90
运输 wet ice
Gene Information human ... EFEMP1(2202)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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