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位置: 首页> 品牌> Sigma-Aldrich> Anti-FEN-1 antibody produced in rabbit

Anti-FEN-1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701665
包装型号
规格纯度
价格
4668.88 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-FEN-1 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human FEN-1

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 monoclonal
形式 liquid
species reactivity rat, human, mouse
浓度 0.23 mg/mL
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号 P39748
运输 wet ice
储存温度 ?20℃
Gene Information human ... FEN1(2237)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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