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位置: 首页> 品牌> Sigma-Aldrich> Anti-FBPase 1, clone 13A8.1 Antibody

Anti-FBPase 1, clone 13A8.1 Antibody

品牌
Sigma-Aldrich
货号
MABC543
规格纯度
clone 13A8.1, from mouse
价格
5426.21 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-FBPase 1, clone 13A8.1 Antibody
Fructose-1,6-bisphosphatase 1, FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, Liver FBPase
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Fructose-1, 6-bisphosphatase 1 (FBPase 1), also known as D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, and encoded by the gene name FBP1 and FBP, belongs to the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations; thus, acting as a rate-limiting enzyme in gluconeogenesis. FBPase 1 has been demonstrated to play a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. FBPase 1 may be involved in modulating glycerol gluconeogenesis in liver. FBPase 1 has been studied as an important regulator of appetite and adiposity. Increased expression of FBPase 1 in liver, after nutrient excess, increases circulating satiety hormones and reduces appetite-stimulating neuropeptides. Therefore, FBPase 1 may be an important target that provides a feedback mechanism to limit weight gain. FBPase 1 is expressed mainly in pancreatic islets.

免疫原

KLH-conjugated linear peptide corresponding to human FBPase 1.

应用

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FBPase 1 in human pancreas tissue.
Anti-FBPase 1, clone 13A8.1 | MABC543 is an antibody against FBPase 1 for use in Western Blotting, Immunohistochemistry (Paraffin).

质量

Evaluated by Western Blotting in mouse stomach tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FBPase 1 in 10 ?g of mouse stomach tissue lysate.

目标描述

~36 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Purified by Ion-Exchange Chromatography
Format: Purified

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 13A8.1, monoclonal
species reactivity mouse, human
technique(s) immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型 IgMκ
NCBI登记号 NP_000498
UniProt登记号 P09467
运输 wet ice
Gene Information human ... FBP1(2203)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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