Anti-EPB41L3 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B is expressed at high levels in the brain and neurons. Adipose tissue, kidney, testis, adrenal gland, and placenta also show high expression of EPB41L3. It is moderately expressed in the lungs and intestines. EPB41L3 gene is located on human chromosome 18p11.31. Protein 4.1B belongs to the protein 4.1 superfamily of proteins. It has an N-terminal 4.1/ezrin/radixin/moesin (FERM) domain.

免疫原

EPB41L3 (AAH06141.1, 1 a.a. ~ 865 a.a) full-length human protein.

Sequence
MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKTDSERTDTAADGETTATEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEEKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED

生化/生理作用

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B helps in linking cellular receptors with the cytoskeleton. It possesses tumor-suppressive action. In human, overexpression of EPB41L3 gene can stimulate apoptosis in breast cancer, non-small cell lung cancer, and meningioma cells.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen ~96.5 kDa
species reactivity	human
technique(s)	western blot: 1 μg/mL
NCBI登记号	BC006141.1
UniProt登记号	Q9Y2J2
运输	dry ice
储存温度	?20℃
Gene Information	human ... EPB41L3(23136)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable