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Anti-ELP3 (C-term) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300151
规格纯度
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-ELP3 (C-term) antibody produced in rabbit
Anti-HELP3
Anti-EC 2.3.1.48
Anti-ELP3
Anti-Elongator complex protein 3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The gene ELP3 (elongator complex protein 3) is mapped to human chromosome 8p21.1. The encoded protein has a HAT (histone acetyltransferase) domain.

免疫原

ELP3 (NP_060561, 473-508)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ELP3.

生化/生理作用

ELP3 (elongator complex protein 3) is a catalytic subunit of the histone acetyltransferase elongator complex. It enhances histone H3 acetylation, thereby regulating gene regulation in neurons. Dysregulation of ELP3 activity causes neuronal disorders, such as familial dysautonomia and amyotrophic lateral sclerosis. It might be a potential acetyltransferase for glucose-6-phosphate dehydrogenase. The ELP3 gene promoter is hypermethylated in invasive ductal breast carcinoma, causing transcriptional inactivation of the gene.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 saturated ammonium sulfate (SAS) precipitated
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号 NP_060561
UniProt登记号 Q9H9T3
运输 dry ice
储存温度 ?20℃
Gene Information human ... ELP3(55140)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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