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Anti-DPAGT1 Antibody

品牌
Sigma-Aldrich
货号
ABS763
规格纯度
from rabbit, purified by affinity chromatography
价格
6022.61 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-DPAGT1 Antibody
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, also known as GlcNAc-1-P transferase (G1PT or GPT) or N-acetylglucosamine-1-phosphate transferase, and encoded by the gene name DPAGT1 or DPAGT2, is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.

免疫原

KLH-conjugated synthetic peptide corresponding to the N-terminus of human DPAGT1.
Epitope: N-terminus

应用

Research Category
Signaling
Anti-DPAGT1 Antibody detects level of DPAGT1 & has been published & validated for use in DPAGT1.
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in mouse kidney tissue lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected DPAGT1 in mouse kidney tissue lysate with and without blocking peptide.

目标描述

~42 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity mouse
technique(s) western blot: suitable
UniProt登记号 Q9H3H5
运输 wet ice
Gene Information human ... DPAGT1(1798)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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