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Anti-DNA ligase IV antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700971
包装型号
规格纯度
价格
4273.48 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-DNA ligase IV antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human DNA Ligase IV

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 monoclonal
形式 liquid
浓度 1.45 mg/mL
technique(s) western blot: 1:500-1:2000
UniProt登记号 P49917
运输 wet ice
储存温度 ?20℃
Gene Information human ... LIG4(3981)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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