Anti-DGKI antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Anti-DGKI Antibody detects endogenous levels of total DGKI protein.
DGKI (Diacylglycerol kinase iota) is a small, integral membrane protein belonging to the type IV diacylglycerol kinase subfamily. It is mapped on chromosome 7q32.3-q33. The members of the DGK family consist of a catalytic domain and at least two cysteine-rich regions. In type IV family members, it has four ankyrin repeats and a carboxy terminal PDZ binding domain.

免疫原

The antiserum was produced against synthesized peptide derived from human DGKI.

Immunogen Range:991-1040

应用

Anti-DGKI, C-Terminal antibody produced in rabbit is suitable for indirect immunofluorescence and western blot.

生化/生理作用

DGKI (Diacylglycerol kinase iota) is mainly involved in the maintenance of intracellular concentration of diacylglycerol by phosphorylating other lipids in addition to DAG. DGKI has been predicted to be a potential gene for tumor suppression in colorectal cancers and mutation in DGKI has been linked to the melanoma.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 116 kDa
species reactivity	rat, human
浓度	~1 mg/mL
technique(s)	ELISA: 1:20000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000
NCBI登记号	O75912
UniProt登记号	O75912
运输	wet ice
储存温度	?20℃
Gene Information	human ... DGKI(9162)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable