您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-CTGF antibody, Mouse monoclonal

Anti-CTGF antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200401
规格纯度
clone CTGF-14, purified from hybridoma cell culture
价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CTGF antibody, Mouse monoclonal
Monoclonal Anti-CTGF antibody produced in mouse
Monoclonal Anti-IBP-8
Monoclonal Anti-CCN2
Monoclonal Anti-CCN family member 2
Monoclonal Anti-Hypertrophic chondrocyte-specific protein 24
Monoclonal Anti-HCS24
Monoclonal Anti-Connective tissue growth factor
Monoclonal Anti-NOV2
Monoclonal Anti-IGFBP8
Monoclonal Anti-IGF-binding protein 8
Monoclonal Anti-Insulin-like growth factor-binding protein 8
Monoclonal Anti-IGFBP-8
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Monoclonal Anti-CTGF (mouse IgG1 isotype) is derived from the hybridoma CTGF-14 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. Connective tissue growth factor (CTGF) gene is mapped to human chromosome 6q23.2. It encodes a splice variant and also known as CCN family member 2 (CCN2). CTGF belongs to the family of regulatory proteins of the extracellular matrix (ECM) and is secreted by endothelial cells. It is expressed in the embryonic stage. The domain regions associated with the CTGF comprise four modules namely: Insulin-like growth factor binding proteins module, von willebrand factor type C repeat, thrombospondin type I repeat and cystine knot associated carboxy-terminal domain.

特异性

Monoclonal Anti-CTGF recognizes human CTGF.

免疫原

immunized with a synthetic peptide corresponding to an internal region of human CTGF (GeneID: 1490), conjugated to KLH. The corresponding sequence differs by a single amino acid in mouse and rat.

应用

Monoclonal Anti-CTGF antibody produced in mouse may be used in immunoblotting and immunoprecipitation.

生化/生理作用

Connective tissue growth factor (CTGF) has been shown to play a role in developmental regulation of chondrogenesis, osteogenesis and angiogenesis, and in pathological processes, including fibrosis and tumorigenesis. CTGF may play an important role in the progression of malignant melanoma and the activation of wingless (WNT) signaling through low-density lipoprotein receptor-related protein 6 (LRP6). Certain polymorphisms in the CTGF gene have been linked with a higher incidence of systemic sclerosis.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

储存及稳定性

For continuous use, store at 2-8℃ for up to one month. For extended storage, freeze at -20oC in working aliquots. Repeated freezingand thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 purified from hybridoma cell culture
antibody product type primary antibodies
克隆 CTGF-14, monoclonal
形式 buffered aqueous solution
分子量 antigen ~38 kDa
species reactivity human
浓度 ~1.0 mg/mL
technique(s) immunoprecipitation (IP): suitable
western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over-expressing CTGF.
同位素/亚型 IgG1
UniProt登记号 P29279
运输 dry ice
储存温度 ?20℃
Gene Information human ... CTGF(1490)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map