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Anti-CSPG4

品牌
Sigma-Aldrich
货号
SAB4301658
规格纯度
affinity isolated antibody
价格
5097.31 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CSPG4
NG2
MCSPG
MCSP
HMW-MAA
MSK16
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Chondroitin sulfate proteoglycan 4 (CSPG4) is commonly known as Melanoma chondroitin sulphate proteoglycan (MCSP). MCSP is a transmembrane protein. MCSP is lower in normal melanocytes. In human chromosome, the gene CSPG4 is localized on 15q24.2.

免疫原

Synthetic peptide corresponding to residues near the C terminal of human chondroitin sulfate proteoglycan 4

生化/生理作用

Chondroitin sulfate proteoglycan 4 (CSPG4) is a cell surface antigen, expressed in most human melanoma and is crucial for tumour progression and invasion. MCSP activates cell division control protein 42 homolog (Cdc42) and Cdc42-associated tyrosine kinase-1 (Ack-1) to form complex, which signals and leads to melanoma progression and metastasis. The complex of MCSP with membrane-type 3 matrix metalloproteinase (MT3-MMP) signals melanoma invasion and proteolysis. MCSP is associated with angiogenesis dependent processes like tumor growth and healing of wound. MCSP plays a key role in regulating chondrosarcoma and provides resistance to chemotherapy. CSPG4 is a prognostic marker for glioblastoma.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous glycerol solution
species reactivity rat, human, mouse
technique(s) immunohistochemistry: 1:20-1:100
western blot: 1:500-1:2000
登记号 NP_001888
UniProt登记号 Q6UVK1
运输 wet ice
储存温度 ?20℃
Gene Information human ... CSPG4(1464)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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