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位置: 首页> 品牌> Sigma-Aldrich> Anti-C1S, C-Terminal antibody produced in rabbit

Anti-C1S, C-Terminal antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4503022
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-C1S, C-Terminal antibody produced in rabbit
Complement component 1 subcomponent s
C1 esterase
C1S
Complement C1s subcomponent
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-C1S Antibody detects endogenous levels of total C1S protein.
The C1S (complement C1s) gene is mapped to human chromosome 12p13 and codes for a subcomponent of C1 complex of the classical pathway.

免疫原

The antiserum was produced against synthesized peptide derived from human C1S.

Immunogen Range:541-590

生化/生理作用

Activation of C1s (complement C1s) along with C1r triggers complement cascade. C1s is responsible for the cleavage of complement component C4 and C2, which is necessary for complete activation of complement system. Studies determined that C1s specifically acts on Val or Leu at P(3) and Ala or Gly residues at P(2) positions. The C1S gene is known to be associated with lupus nephritis, with low gene expression observed in mice.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

MDL编号 MFCD02685982
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 76 kDa
species reactivity human
浓度 ~1 mg/mL
technique(s) ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 P09871
UniProt登记号 P09871
运输 wet ice
储存温度 ?20℃
Gene Information human ... C1S(716)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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