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位置: 首页> 品牌> Sigma-Aldrich> Anti-C1QB, C-Terminal antibody produced in rabbit

Anti-C1QB, C-Terminal antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4502986
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-C1QB, C-Terminal antibody produced in rabbit
Complement C1q subcomponent subunit B
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The C1QB (complement C1q B chain) gene is mapped to human chromosome 1p36.12 and codes for the subcomponent of C1q protein, which is part of C1 complex of the classical pathway. The encoded protein is predominantly expressed in neurons and glia. It is localized to the growing synapses. The encoded protein is a hexameric molecule consisting of three distinct types of 18 polypeptide chains.
Anti-C1QB Antibody detects endogenous levels of total C1QB protein.

免疫原

The antiserum was produced against synthesized peptide derived from human C1QB.

Immunogen Range:161-210

生化/生理作用

The protein encoded by C1QB (complement C1q B chain) gene is involved in synapse formation and offers neuroprotection in the central nervous system. In response to a number of immune and nonimmune ligands, C1q protein activates proteases C1r and C1s in order to trigger classical complement pathway. C1q protein is regarded as a major component of the humoral innate immune defense. C1q carries out opsonophagocytosis, inflammation, and cytolysis to eliminate pathogenic microorganism and harmful apoptotic cells. Mutations in the gene causes systemic lupus erythematosus. Variation in the gene is also linked to rheumatoid schizophrenia, arthritis, amyloidotic polyneuropathy, metastasis of cancer.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 26 kDa
species reactivity human
浓度 ~1 mg/mL
technique(s) ELISA: 1:40000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号 P02746
UniProt登记号 P02746
运输 wet ice
储存温度 ?20℃
Gene Information human ... C1QB(713)

安全信息

储存分类代码 10 - Combustible liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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