Anti-Complement C3a Antibody, clone H13

半岛bd体育手机客户端 说明

特异性

The antibody recognizes an epitope on the alpha-chain of Complement C3 (Western blot). The antibody inhibits the anaphylactic function of C3a: the capacity of C3a to induce serotonin release from thrombocytes in vitro is inhibited; similarly, treatment of C3a with the antibody inhibits the C3a-induced skin reaction in vivo. The antibody is, in combination with antibodies to the C3b fragment, an excellent control for distinguishing ubiquitous or nonspecifically bound native C3 from the biologically active C3 fragment. Nonactivated C3 still bears the C3a determinant, whereas activated C3 (C3b, C3d) is C3a-negative. It is therefore useful for immunopathological assays (demonstration of C3 deposition in biopsies) and for C3a assays.

免疫原

Human complement component C3

应用

Research Sub Category
Immunoglobulins & Immunology
This Anti-Complement C3a Antibody, clone H13 is validated for use in ELISA, IH, WB for the detection of Complement C3a.
Research Category
Inflammation & Immunology

外形

Protein A purified immunoglobulin lyophilized from PBS, pH 7.4, containing 0.5% BSA and 0.09% sodium azide. Reconstitute with 1 mL distilled water.
Format: Purified

储存及稳定性

Maintain at 2°-8°C for up to 12 months from date of receipt.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	H13, monoclonal
species reactivity	human, rabbit, guinea pig
manufacturer/tradename	Chemicon?
technique(s)	ELISA: suitable immunohistochemistry: suitable western blot: suitable
同位素/亚型	IgG2b
NCBI登记号	NM_000064.2
UniProt登记号	P01024
运输	wet ice

安全信息

象形图
警示用语：	Warning
危险声明	H312 + H332 - H412
预防措施声明	P261 - P271 - P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
储存分类代码	11 - Combustible Solids
WGK	WGK 3