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位置: 首页> 品牌> Sigma-Aldrich> Anti-Collagen IV α3 (Cleaved-Pro1426) antibody produced in rabbit

Anti-Collagen IV α3 (Cleaved-Pro1426) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500378
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Collagen IV α3 (Cleaved-Pro 1426) antibody produced in rabbit
Goodpasture antigen
Collagen α-3(IV) chain
COL4A3
CO4A3
Tumstatin
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Collagen type IV alpha 3 chain (COL4A3) gene with 52 exons, codes for the α3 chain of type IV collagen. COL4A3 protein is the vital structural protein in the basement membrane. COL4A3 gene is located on human chromosome 2q36.3. Anti-Collagen IV α3 (cleaved-pro1426) antibody detects endogenous levels of fragment of activated collagen IV α3 (cleaved-pro1426) protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Collagen IV alpha3.

Immunogen Range:1407-1456

生化/生理作用

Type IV collagen plays a key role in cell adhesion, proliferation, migration, survival, and differentiation. It maintains the assembly and mechanical stability by acting as a scaffold. Collagen type IV alpha 3 chain (COL4A3) mutations are associated with Alport syndrome (AS). Heterozygous mutations in the COL4A4 gene are observed in individuals with benign familial hematuria (BFH). Alterations in the COL4A3 gene also result in diabetic kidney disease from maturity-onset diabetes.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 27 kDa
species reactivity human
浓度 ~1 mg/mL
technique(s) ELISA: 1:40000
western blot: 1:500-1:1000
NCBI登记号 Q01955
UniProt登记号 Q01955
运输 wet ice
储存温度 ?20℃
Gene Information human ... COL4A3(1285)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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