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位置: 首页> 品牌> Sigma-Aldrich> Anti-CNOT3 antibody produced in rabbit

Anti-CNOT3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV34318
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-CNOT3 antibody produced in rabbit
Anti-CCR4-NOT transcription complex, subunit 3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CNOT3 is a subunit of the CCR4-NOT transcription complex. This subunit can bind to the PRPF31 promoter and mediate transcriptional repression. It acts as a modifier gene and controls the effects of PRPF31 mutations in retinitis pigmentosa. CNOT3 mutations have also been implicated in T-cell acute lymphoblastic leukemia (T-ALL).
Rabbit Anti-CNOT3 antibody recognizes bovine, human, mouse, rat, zebrafish, canine, and rabbit CNOT3.

免疫原

Synthetic peptide directed towards the N terminal region of human CNOT3

应用

Rabbit Anti-CNOT3 antibody can be used for western blot applications at a concentration of 0.5 μg/ml.

生化/生理作用

CNOT3 is a protein component of CCR4-NOT protein complex. Yeast CCR$-NOT is a global regulator of RNA polymerase II transcription. It is comprised of yeast NOT1 to NOT5, yeast CCR4 and additional proteins like yeast CAF1.

序列

Synthetic peptide located within the following region: QFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRML

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 82 kDa
species reactivity horse, rat, dog, bovine, guinea pig, mouse, human, rabbit
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_055331
UniProt登记号 O75175
运输 wet ice
储存温度 ?20℃
Gene Information human ... CNOT3(4849)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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