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Anti-CNGB1 Antibody, clone 5A5.1

品牌
Sigma-Aldrich
货号
MABN282
规格纯度
clone 5A5.1, 1 mg/mL, from mouse
价格
5520.38 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-CNGB1 Antibody, clone 5A5.1
Cyclic nucleotide-gated cation channel beta-1, Cyclic nucleotide-gated cation channel 4, CNG channel 4, CNG-4, CNG4, Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CNGB1, also known as Cyclic nucleotide-gated cation channel beta-1, Cyclic nucleotide-gated cation channel 4 (CNG4), Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-1, or Glutamic acid-rich protein (GARP), and encoded by the gene CNGB1/CNCG2/CNCG3L/CNCG4/RCNC2, is a subunit of cyclic nucleotide-gated (CNG) channels which are nonselective cation channels expressed in retinal and olfactory neurons. The CNG channels play important roles in both visual and olfactory signal transduction. When associated with CNGA1, CNGB1 is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. CNGB1 is localized in the plasma membranes of expressing cells and mediates the ion transport of the channel. Mutations in CNGB1 are associated with the genetic disease retinitis pigmentosa 45 that is a progressive vision disease associated with the loss of rod and cone photoreceptors.

免疫原

GST-tagged recombinant protein corresponding to human CNGB1.

应用

Research Category
Neuroscience
Detect CNGB1 using this Anti-CNGB1 Antibody, clone 5A5.1 validated for use in western blotting.
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in Y79 cell lysate.

Western Blotting Analysis: 1.0 ?g/mL of this antibody detected CNGB1 in 10 ?g of Y79 cell lysate.

目标描述

~140 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified
Format: Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 5A5.1, monoclonal
species reactivity human
浓度 1 mg/mL
technique(s) western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_001129111
UniProt登记号 Q14028
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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