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Anti-CLEC2A Antibody

品牌
Sigma-Aldrich
货号
ABC328
规格纯度
from rabbit, purified by affinity chromatography
价格
5075.49 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-CLEC2A Antibody
C-type lectin domain family 2 member A, Keratinocyte-associated C-type lectin, KACL, Proliferation-induced lymphocyte-associated receptor, PILAR, UNQ579, PRO19597
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

C-type lectin domain family 2 member A (CLEC2A) is also called proliferation-induced lymphocyte-associated receptor (PILAR) and Keratinocyte-associated C-type lectin (KACL). CLEC2A is involved in modulating T-cell expansion. It is a 32 kDa single-pass type II membrane protein that belongs to the CTL/CTLD superfamily. CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes and naive CD4(+) T cells. Modulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer. CLEC2A is associated with expansion of TCR-stimulated T-cells, modulates the capacity of T-cells to home to lymph nodes through SELL, and facilitates immune recognition of keratinocytes by stimulating natural killer cell mediated cytotoxicity.

免疫原

KLH-conjugated linear peptide corresponding to human CLEC2A.

应用

Research Sub Category
Apoptosis - Additional
Anti-CLEC2A Antibody is a highly specific rabbit polyclonal antibody, that targets CLEC2A & has been tested in western blotting.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting/Peptide Inhibition Assay in K562 cell lysate.

Western Blotting/Peptide Inhibition Analysis: 1 ?g/mL of this antibody detected CLEC2A in 15 ?g of K562 cell lysate.

目标描述

~32 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~19 kDa and ~20 kDa

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
K562 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human
technique(s) western blot: suitable
UniProt登记号 Q6UVW9
运输 wet ice

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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