Anti-Chymase Antibody, clone B7

半岛bd体育手机客户端 说明

一般描述

Mast cell chymase (EC 3.4.21.39), a member of the granzyme subfamily of the S1 family of peptidases, cleaves C-terminal to Phenylalanine, Tyrosine, Tryptophan, and Leucine residues (in order of preference). Chymase is stored in Mast cell granules within the cell and is the major secreated Mast cell protease. Secreated Mast cell chymase is believed to be involved in extracellular matrix degradation, vasoactive peptide generation, and regulation of gland secreation.

特异性

Reacts with human mast cell chymase.

免疫原

Chymase purified from human skin.

应用

Research Sub Category
Inflammation & Autoimmune Mechanisms
Dot blotting: 0.5-1.0 μg/mL.

Immunohistochemistry: 0.5-1.0 μg/mL. For optimal results, tissues or cytospin preparations should be fixed in Carnoy′s Fluid (60% ethanol, 30% chloroform, 10% glacial acetic acid). Not recommended for use on formaldehyde fixed tissue.

Not recommended for use on Western blots.

Optimal working dilutions must be determined by end user.
Anti-Chymase Antibody, clone B7 is an antibody against Chymase for use in DB, IH.
Research Category
Inflammation & Immunology

外形

Purified by protein G affinity chromatography. Liquid in PBS with 20% glycerol, pH 7.4.
Format: Purified

储存及稳定性

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt. Antibody may also be stored at -20?C in undiluted aliquots.

分析说明

Control
POSITIVE CONTROL: lung, heart, skin, placenta.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	B7, monoclonal
species reactivity	human
manufacturer/tradename	Chemicon?
浓度	2.4 mg/mL
technique(s)	dot blot: suitable immunohistochemistry: suitable
同位素/亚型	IgG1κ
适用性	not suitable for Western blot
NCBI登记号	NM_001836.2
UniProt登记号	P23946
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable