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位置: 首页> 品牌> Sigma-Aldrich> Anti-Cholesterol-24 Hydroxylase Antibody, clone1A7

Anti-Cholesterol-24 Hydroxylase Antibody, clone1A7

品牌
Sigma-Aldrich
货号
MAB2259
规格纯度
clone 1A7, from mouse
价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-Cholesterol-24 Hydroxylase Antibody, clone1A7
Cytochrome P450 46A1, cholesterol 24-hydroxylase, cytochrome P450, family 46, cytochrome P450, family 46, subfamily A, polypeptide 1, cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

In enzymology, a cholesterol 24-hydroxylase (EC 1.14.13.98) is an enzyme that catalyzes the chemical reaction:
cholesterol + NADPH + H+ + O2 --> (24S)-24-hydroxycholesterol + NADP+ + H2O. Cholesterol 24-hydroxylase, a cytochrome P450 (CYP46A1), is expressed at 100-fold higher levels in the brain than in the liver. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. Studies indicate that cholesterol 24-hydroxylase constitutes a major tissue-specific pathway for cholesterol turnover in the brain (Lund, 2003).

特异性

This antibody recognizes cholesterol-24 hydroxylase.

免疫原

His-tagged recombinant protein corresponding to human cholesterol-24 hydroxylase.
Epitope: unknown

应用

Detect Cholesterol-24 Hydroxylase using this Anti-Cholesterol-24 Hydroxylase Antibody, clone1A7 validated for use in WB, IP, IC, IH.
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience

质量

Evaluated by Western Blot in Cholesterol-24 hydroxylase mouse brain lysate.

Western Blot Analysis: 1 ?g/ml of this antibody detected Cholesterol-24 hydroxylase on 10 ?g of Cholesterol-24 hydroxylase mouse brain lysate.

目标描述

~ 54 kDa

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 1A7, monoclonal
species reactivity mouse
species reactivity (predicted by homology) human (based on 100% sequence homology), rabbit (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s) immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_006659
UniProt登记号 Q9Y6A2
运输 wet ice
Gene Information human ... CYP46A1(10858)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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