Anti-CD3 antibody, Rabbit monoclonal

半岛bd体育手机客户端 说明

一般描述

CD3E (CD3e molecule) gene is mapped to human chromosome 11q23.3. This gene encodes fora subunit of T-cell regulator (TCR) protein complex. It possesses IgG (immunoglobulin G)-like extracelluar domain at the N-terminal, a transmembrane domain, a peptide bridge and an immunoreceptor tyrosine-based activation motif (ITAM) towards the cytoplasm. The protein also contains basic residue-rich sequence (BRS).
This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.

免疫原

Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.

应用

Anti-CD3 antibody, Rabbit monoclonal has been used in immunohistochemistry.

生化/生理作用

CD3E (CD3e molecule) gene is associated with actin cytoskeletal rearrangement, through activation of a number of signaling pathways. CD3E is essential for membrane binding of T-cell regulator (TCR) protein complex.

特点和优势

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外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
重组	expressed in proprietary host
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	SP162, monoclonal
species reactivity	human (tested)
species reactivity (predicted by homology)	chicken, rabbit, dog, bovine, rat, mouse, pig
technique(s)	flow cytometry: 1:150 immunoblotting: 1:150 immunohistochemistry: 1:150
同位素/亚型	IgG
UniProt登记号	P07766
运输	wet ice
储存温度	2-8℃
Gene Information	human ... CD3E(916)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable