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位置: 首页> 品牌> Sigma-Aldrich> Anti-CD39 Antibody, clone 5E12

Anti-CD39 Antibody, clone 5E12

品牌
Sigma-Aldrich
货号
MABN645
规格纯度
clone 5E12, 1 mg/mL, from rat
价格
5052.86 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-CD39 Antibody, clone 5E12
Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen, CD39
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CD39 (EC 3.6.1.5; also known as Ecto-apyrase, Ecto-ATPase 1, Ecto-ATPDase1 , Ecto-ATP diphosphohydrolase 1, Ectonucleoside triphosphate diphosphohydrolase 1, Lymphoid cell activation antigen, NTPDase 1) is encoded by the Entpd1 or Cd39 gene (Entrez Gene ID 12495) in murine species. CD39 is a cell surface nucleotide-metabolizing enzyme that hydrolyzes extracellular purine NTP and NDP. E. coli infection is reported to induce CD39 promoter activity in macrophages, resulting in an upregulated CD39 expression during sepsis in mice, while CD39 knockdown increases mortality among mice with polymicrobial sepsis (PMID 25318479). Anti-CD39, clone 5E12 binds the murine CD39 (P55772) extracellular domain and is demonstrated to selectively stain murine macroglia by flow cytometry (PMID 22863620).

免疫原

Epitope: extracellular domain
Whole cells with surface CD39.

应用

Research Category
Neuroscience
Flow Cytometry Analysis: A representative lot detected CD39 in CD11b+ cells (Butovsky, O., et al. (2012). J. Clin. Invest. 122(9):3063-3087).
Anti-CD39 Antibody, clone 5E12 is an antibody against CD39 for use in Flow Cytometry.
Research Sub Category
Developmental Signaling

质量

Evaluated by Flow Cytometry in CD11b+ mouse splenocytes.

Flow Cytometry Analysis: Various dilutions of this antibody detected CD39 in CD11b+ mouse splenocytes.

目标描述

70-100 kDa calculated

外形

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
抗体形式 purified antibody
antibody product type primary antibodies
克隆 5E12, monoclonal
species reactivity mouse
浓度 1 mg/mL
technique(s) flow cytometry: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NP_033978
UniProt登记号 P55772
运输 wet ice

安全信息

储存分类代码 10-13 - German Storage Class 10 to 13

Sigma-Aldrich

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