半岛bd体育手机客户端 说明
一般描述
This rat monoclonal antibody Anti-CD44 (human/mouse), APC-Cy7, clone IM7 validated for use in western blotting, IP, IHC & Flow Cytometry for the detection of CD44.
The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.
质量
The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.25 μg of this antibody detected CD44 in one million C57Bl/6 splenocytes.
外形
Size Exclusion Chromatography
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.44 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | rat |
偶联物 | APC-Cy7 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | IM7, monoclonal |
species reactivity | human, mouse |
包装 | antibody small pack of 25 μg |
浓度 | 0.2 mg/mL |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
同位素/亚型 | IgG2bκ |
UniProt登记号 | P15379 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich