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位置: 首页> 品牌> Sigma-Aldrich> Anti-CD127 (IL-7Ra) Antibody (mouse), Biotin, clone A7R34

Anti-CD127 (IL-7Ra) Antibody (mouse), Biotin, clone A7R34

品牌
Sigma-Aldrich
货号
MABF536
规格纯度
clone A7R34, 0.5 mg/mL, from rat
价格
1415.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CD127 (IL-7Ra) Antibody (mouse), Biotin, clone A7R34
Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CD217
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).
This rat monoclonal antibody Anti-CD127 (IL-7Ra) (mouse), Biotin, clone A7R34 validated for use in IP, Flow Cytometry & IHC for the detection of CD127 (IL-7Ra).

质量

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.06 ?g of this antibody detected CD127 (IL-7Ra) in one million C57Bl/6 splenocytes.

外形

Size Exclusion Chromatography

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
偶联物 biotin conjugate
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 A7R34, monoclonal
species reactivity mouse
包装 antibody small pack of 25 μg
浓度 0.5 mg/mL
technique(s) flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同位素/亚型 IgG2aκ
UniProt登记号 Q60943
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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