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位置: 首页> 品牌> Sigma-Aldrich> Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10

Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10

品牌
Sigma-Aldrich
货号
MABN487
规格纯度
clone N55/10, from mouse
价格
6022.61 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10
Cav3.2 Calcium Channel Subunit, Voltage-dependent T-type calcium channel subunit alpha-1H, Low-voltage-activated calcium channel alpha1 3.2 subunit, Voltage-gated calcium channel subunit alpha Cav3.2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Voltage-gated calcium channel subunit alpha Cav3.2 is also called Voltage-dependent T-type calcium channel subunit alpha-1H and Low-voltage-activated calcium channel alpha 1 3.2 subunit. Voltage-gated calcium channel subunit alpha Cav3.2 and other voltage-sensitive calcium channels (VSCC) are involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Voltage-gated calcium channel subunit alpha Cav3.2 is expressed in kidney, liver, heart, brain, and isoform 2 appears to be testis specific. Voltage-gated calcium channel subunit alpha Cav3.2 defects can increase susceptibility to epilepsy, idiopathic generalized type 6 (EIG6) and epilepsy, childhood absence type 6 (ECA6).

特异性

This antibody does not cross react with human Cav3.1 Calcium Channel Subunit (Prof. J. Trimmer, University of California, Davis.).

免疫原

Recombinant protein corresponding to human Cav3.2 Calcium Channel Subunit.

应用

Research Sub Category
Synapse & Synaptic Biology
Detect Cav3.2 using this mouse monoclonal antibody, Anti-Cav3.2 Calcium Channel Subunit Antibody & clone N55/10 validated for use in western blotting.
Research Category
Neuroscience
Immunohistochemistry Analysis: A representative lot detected Cav3.2 Calcium Channel Subunit in wild type mice and demonstrated a loss of signal in Cav3.2 knock out mice (Prof. J. Trimmer, University of California, Davis.).

Western Blotting Analysis: A representative lot detected Cav3.2 Calcium Channel Subunit in HEK293 cell lysates expressing Flag-tagged Cav3.2 and demonstrated a loss of signal in HEK293 cell lysates expressing Flag-tagged Kv2.1 and Flag-tagged Cav3.1 (Prof. J. Trimmer, University of California, Davis.).

质量

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 ?g/mL of this antibody detected Cav3.2 Calcium Channel Subunit in 10 ?g of NIH/3T3 cell lysate.

目标描述

~260 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
NIH/3T3 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified antibody
antibody product type primary antibodies
克隆 N55/10, monoclonal
species reactivity mouse
species reactivity (predicted by homology) human (immunogen homology)
technique(s) western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_001005407
UniProt登记号 O95180
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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