Anti-CASPASE-12 (ab1) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex.

免疫原

a peptide corresponding to amino acids 2-17 of murine caspase-12.

应用

Anti-CASPASE-12 (ab1) antibody produced in rabbit has been used in western blotting.

生化/生理作用

Murine caspase 12 (CASP12) is activated during endoplasmic reticulum stress and activates other caspases which act on substrates, ultimately leading to apoptosis. The protein has been shown to be activated during progression of retinal degeneration in animal models. In mice models, CASP12 has been shown to cause neuronal death resulting from ischemia/reperfusion.

联系

The action of this antibody can be blocked using blocking peptide SBP2325.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03454856
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	predicted mol wt 46 kDa
species reactivity	rat, mouse, human
technique(s)	immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable
UniProt登记号	O08736
运输	dry ice
储存温度	?20℃
Gene Information	mouse ... Casp12(12364)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable