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Anti-C/EBP-α antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500110
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-C/EBP-α antibody produced in rabbit
C/EBP α
CCAAT/enhancer binding protein α
CEBPA
CCAAT/enhancer binding protein (C/EBP) α
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CCAAT/enhancer-binding protein α (C/EBPα) is encoded by the gene mapped to human chromosome 19q13.1. The encoded protein belongs to the basic leucine zipper (bZIP) family of transcription factors. CEBPA is highly expressed in differentiated tissues.
Anti-C/EBP-α Antibody detects endogenous levels of total C/EBP-α protein.

免疫原

The antiserum was produced against synthesized peptide derived from human C/EBP-alpha.

Immunogen Range:6-55

生化/生理作用

The transcription factor CCAAT/enhancer-binding protein α (C/EBPα) plays an essential role in tumor progression. It blocks β-catenin to repress lung adenocarcinoma cell invasion and migration. CEBPA is implicated in the regulation of hematopoiesis and terminal differentiation of various cell types like adipocytes, hepatocytes and different epithelial cells. Variations in the gene expression has been observed in 5–10% of cases of acute myeloid leukemia (AML).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 37 kDa
species reactivity human, rat, mouse
浓度 ~1 mg/mL
technique(s) ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 P49715
UniProt登记号 P49715
运输 wet ice
储存温度 ?20℃
Gene Information human ... CEBPA(1050)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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