Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody

半岛bd体育手机客户端 说明

一般描述

C-X-C chemokine receptor type 5 (CXCR5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15) is a G-protein coupled cytokine receptor that binds selectively to the CXCL13 (B lymphocyte chemoattractant) ligand, and mediates the development and function of the immune system. It is expressed in mature B cells, and facilitates the migration of B cells into follicles of the splenic white pulp, and enables deposition of antigen on follicular dendritic cells. It is also involved in the development of lymph nodes and Peyer’s patches. Previous studies have reported that the expression of CXCR5 increases in rheumatoid arthritis.

特异性

This antibody recognizes the cytoplasmic domain of C-X-C chemokine receptor type 5 (CXCR5).

免疫原

Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human C-X-C chemokine receptor type 5 (CXCR5).

应用

Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Immunohistochemistry Analysis: A 1:1,000 dilution from representative lot detected C-X-C chemokine receptor type 5 (CXCR5) in mouse frontal cortex neurons and mouse spleen lymphocytes.
Anti-C-X-C chemokine receptor type 5 (CXCR5) Antibody is an antibody against C-X-C chemokine receptor type 5 (CXCR5) for use in Western Blotting, IHC(P).

质量

Evaluated by Western Blot in SH-SY5Y cell lysate.

Western Blot Analysis: 0.1 ?g/mL of this antibody detected C-X-C chemokine receptor type 5 (CXCR5) in 10 ?g of SH-SY5Y cell lysate.

目标描述

~51 / 38 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing with molecular weights ~42 and ~37 kDa The calculated molecular weight of this protein is 42 kDa, but can be observed at ~51 kDa due to high glycosylation.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
SH-SY5Y cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human, mouse
technique(s)	immunohistochemistry: suitable (paraffin) western blot: suitable
NCBI登记号	NP_001707
UniProt登记号	P32302
运输	wet ice
Gene Information	human ... CXCR5(643)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable