Anti-Axin2, clone cond4-1D5 Antibody

半岛bd体育手机客户端 说明

一般描述

Axin-2, or Axis inhibition protein 2, is an inhibitor of the Wnt signaling pathway that down-regulates beta-catenin and APC through phosphorylation. Axin-2 abnormalities are linked to defective mismatch repair and have been found to be involved in colorectal cancer (CRC) and oligodontia-colorectal cancer syndrome (ODCRCS). Axin-2 can be found in brain and lymphoblast tissues.

特异性

This monoclonal antibody recognizes both endogeneous and overexpressed Axin2 and does not cross-react with Axin1

免疫原

Linear peptide corresponding to Human Axin 2.

应用

Immunocytochemistry Analysis: 20 μg/mL of this antibody from a representative lot detected Axin2 in HeLa, HEK293 and NIH-3T3 cells.
Western Blotting Analysis: A representative lot of this antibody detected Axin2 in SW 480 cell lines
Research Sub Category
General Post-translation Modification
This Anti-Axin2, clone cond4-1D5 Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of Axin2.
Research Category
Signaling

Apoptosis & Cancer

质量

Evaluated by Western Blotting in HCT116 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected Axin2 in 10 ?g of HCT116 cell lysate.

目标描述

~ 95 kDa observed

外形

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	rat
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	cond4-1D5, monoclonal
species reactivity	human
technique(s)	immunocytochemistry: suitable western blot: suitable
同位素/亚型	IgG2aκ
NCBI登记号	NP_004646
UniProt登记号	Q9Y2T1
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable