Anti-Avian Influenza Neuraminidase antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Avian Influenza Neuraminidase Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.

免疫原

Avian influenza neuraminidase antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the avian influenza neuraminidase protein.Efforts were made to use relatively conserved regions as the antigen.The immunogen is located within the last 50 amino acids of Avian Influenza Neuraminidase.

应用

Avian influenza neuraminidase antibody can be used for the detection of the avian influenza neuraminidase protein from the H5N1 strain of Avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.

外形

Supplied in PBS containing 0.02% sodium azide.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	influenza A virus (avian)
浓度	1 mg/mL
technique(s)	ELISA: suitable
同位素/亚型	IgG
UniProt登记号	Q710U6
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable