Anti-ATP2C1 Antibody

半岛bd体育手机客户端 说明

一般描述

Calcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes.

特异性

This antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa.

免疫原

KLH-conjugated linear peptide corresponding to human ATP2C1.

应用

Anti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 5 ?g/mL from a representative lot detected ATP2C1 in mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

质量

Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 ?g/mL of this antibody detected ATP2C1 in 15 ?g of mouse brain tissue lysate.

目标描述

~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa Uncharacterized bands may appear in some lysate(s).

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	mouse
species reactivity (predicted by homology)	human (immunogen homology)
technique(s)	immunohistochemistry: suitable western blot: suitable
UniProt登记号	P98194
运输	wet ice
Gene Information	human ... ATP2C1(27032)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable