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Anti-Arginase-1 antibody, Rabbit monoclonal

品牌
Sigma-Aldrich
货号
SAB5500008
规格纯度
recombinant, expressed in proprietary host, clone SP156, affinity isolated antibody
价格
4433.28 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Arginase-1 antibody, Rabbit monoclonal
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Arginase 1 (ARG1) gene with eight exons and seven introns, spanning 10-15 kb on genomic DNA, is localized on human chromosome 6q23.2. The protein consists of 322 amino acids and is expressed in the liver, red blood cells, lactating mammalian glands and the kidney.
Arginase-1 (ARG1) catalyzes the hydrolysis of L-arginine into ornithine and urea, a critical step for the urea cycle. Defects in ARG1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia. There are several isoforms of mammalian arginase. The type I isoform, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Hepatocellular carcinoma usually shows higher protein expression of ARG1 than normal liver cells.

免疫原

Synthetic peptide derived from the C-terminus of human arginase-1 protein.

生化/生理作用

In addition to urea cycle, arginase 1 (ARG1) is also implicated in various cellular processes, such as macrophage-mediated cytotoxicity and regulation of immune response. The encoded protein is also involved in allergen challenged lungs, in autoimmune inflammation in the central nervous system and in acute liver injury.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
重组 expressed in proprietary host
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 SP156, monoclonal
species reactivity human (tested)
species reactivity (predicted by homology) pig, bovine, rabbit
technique(s) immunohistochemistry: 1:100
同位素/亚型 IgG
UniProt登记号 P05089
运输 wet ice
储存温度 2-8℃
Gene Information human ... ARG1(383)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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