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位置: 首页> 品牌> Sigma-Aldrich> Anti-AP2M1 antibody produced in chicken

Anti-AP2M1 antibody produced in chicken

品牌
Sigma-Aldrich
货号
SAB3500044
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-AP2M1 antibody produced in chicken
Anti-AP-2 mu-1
Anti-AP50
Anti-Adaptor-related protein complex 2 mu 1
Anti-CLAPM1
Anti-u2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

AP2M1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human AP2M1.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.

联系

The action of this antibody can be blocked using blocking peptide SBP3500044.

外形

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD02262538
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 chicken
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity rat, human, mouse
technique(s) immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号 NP_004059
UniProt登记号 Q96CW1
运输 dry ice
储存温度 ?20℃
Gene Information human ... AP2M1(1173)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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