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Anti-ALOX5 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701424
包装型号
规格纯度
价格
4668.88 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-ALOX5 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

免疫原

A synthesized peptide derived from human ALOX5

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 monoclonal
形式 liquid
species reactivity mouse, human, rat
浓度 1.45 mg/mL
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号 P09917
运输 wet ice
储存温度 ?20℃
Gene Information human ... ALOX5(240)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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