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位置: 首页> 品牌> Sigma-Aldrich> Anti-Aldh1L1 Antibody, clone N103/39

Anti-Aldh1L1 Antibody, clone N103/39

品牌
Sigma-Aldrich
货号
MABN495
规格纯度
clone N103/39, from mouse
价格
6022.61 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Aldh1L1 Antibody, clone N103/39
Cytosolic 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1

FBP-CI
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Aldh1L1, also known as 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH), is a multidomain protein that is found in liver cytosol and also serves as a CNS astrocyte marker. Aldh1L1 is comprised of two functionally unrelated domains, an aldehyde dehydrogenase-homologous domain and a folate-binding hydrolase domain. These two domains are thought to be connected by a 100-residue linker. It is known to induce phosphorylation of p53 at Ser6, which is a critical step in stimulating apoptosis.

特异性

This Aldh1L1 monoclonal antibody does not exhibit cross-reactivity toward Aldh1L2.

免疫原

Recombinant full-length rat Aldh1L1.

应用

Anti-Aldh1L1, clone N103/39 is an antibody targeting the Aldh1L1 protein, validated for use in Immunofluorescence, Immunohistochemistry, and Western Blotting.
Research Sub Category
Sensory & PNS
Western Blot Analysis: 0.5 ?g/mL from a representative lot detected Aldh1L1 in 10 ?g of human brain tissue lysate.

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Aldh1L1 rat cerebral cortex tissue and human pons/midbrain tissue.

Immunofluorescence Analysis: A representative lot detected Aldh1L1 in rat cortex and cerebellum tissue.
Research Category
Neuroscience

质量

Evaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected Aldh1L1 in 10 ?g of mouse brain tissue lysate.

目标描述

~99 kDa observed

外形

Format: Purified
Purified mouse IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 N103/39, monoclonal
species reactivity human, rat, mouse
technique(s) immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_071992
UniProt登记号 P28037
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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