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Anti-AIF antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700185
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-AIF antibody produced in rabbit
CMTX4
COXPD6
PDCD8
CMT2D
NAMSD
NADMR
AIFM1
COWCK
AIF
DFNX5
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_004199.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 26
28
35
66
species reactivity human, mouse, rat
浓度 1.01 mg/ml
technique(s) immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000
UniProt登记号 O95831
运输 wet ice
储存温度 ?20℃
Gene Information human ... AIFM1(9131)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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