Anti-ADAM10 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

ADAM metallopeptidase domain 10 or A disintegrin and metalloprotease 10 (ADAM10) is a transmembrane protein which is widely distributed. It consists of an amino-terminal signal sequence, a prodomain, a metalloprotease domain, a disintegrin domain, a cysteine-rich region, a transmembrane region and a cytoplasmic tail. The gene encoding this protein is localized on human chromosome 15q21.3.

免疫原

ADAM10 antibody was raised against a peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid (2,4).

生化/生理作用

ADAM metallopeptidase domain 10 (ADAM10) activates Notch proteins and has a role in embryonic development. It functions as a molecular scissor and cleaves the extracellular domains of proteins. The protein is a therapeutic target for a variety of diseases and malignancies.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500181.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03096586
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	predicted mol wt 85 kDa
species reactivity	human
technique(s)	immunocytochemistry: suitable immunofluorescence: suitable indirect ELISA: suitable western blot: suitable
NCBI登记号	NP_001101
UniProt登记号	O14672
运输	dry ice
储存温度	?20℃
Gene Information	human ... ADAM10(102)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable