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Anti-ACE2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500978
规格纯度
affinity isolated antibody
价格
6523.48 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-ACE2 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Angiotensin-converting enzyme-2 (ACE2) gene is mapped to human chromosome Xp22.2. The gene codes for a membrane-associated and secreted enzyme. Ace 2 is a human homolog of angiotensin-converting enzyme (ACE) and is found mainly on endothelium. In humans, Ace2 is exclusively expressed in heart, kidney, and testis. The protein is characterized with an N-terminal PD and a C-terminal collectrin-like domain (CLD).

免疫原

Antibody was raised against a synthetic peptide corresponding to amino acids near the N terminus of human ACE2.

生化/生理作用

Angiotensin-converting enzyme-2 (ACE2) aids in maturation of angiotensin (Ang) by converting Ang I to Ang1-9. It may also play a role in the local renin-angiotensin system (RAS) in heart and kidney. Ace 2 serves as a functional receptor for severe acute respiratory syndrome–coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2), which is responsible for causing coronavirus disease 2019 (COVID-19). Reduced expression of Ace 2 might cause cardiovascular diseases.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500978.

外形

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
浓度 1 mg/mL
technique(s) ELISA: suitable
immunoblotting: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
NCBI登记号 NP_068576
UniProt登记号 Q9BYF1
运输 wet ice
储存温度 ?20℃
Gene Information human ... ACE2(59272)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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