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位置: 首页> 品牌> Sigma-Aldrich> Anti-4E-BP1 antibody produced in rabbit

Anti-4E-BP1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500736
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-4E-BP1 antibody produced in rabbit
Eukaryotic translation initiation factor 4E binding protein 1
EIF4EBP1
4EBP1
Insulin-stimulated EIF-4E binding protein PHAS-I
P/OKCL.6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-4E-BP1 Antibody detects endogenous levels of total 4E-BP1 protein.
The gene E1F4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) is located on human chromosome 8p11. 4E-BP1 is a multifactor regulated multifunctional protein. It belongs to the translation repressor protein family.

免疫原

The antiserum was produced against synthesized peptide derived from human 4E-BP1.

Immunogen Range:30-79

应用

Anti-4E-BP1 antibody has been used in western blotting.

生化/生理作用

E1F4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) is involved in protein synthesis, cell growth and survival. Phosphorylation of E1F4EBP1 releases it from eIF4E (eukaryotic translation initiation factor 4E), thereby resulting in cap-dependent translation. E1F4EBP1 is also involved in tumorigenesis and the gene is overexpressed in various carcinomas. It also serves as a substrate for mTORC1 (mammalian target of rapamycin complex 1).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD04040379
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 12 kDa
species reactivity rat, mouse, human
浓度 ~1 mg/mL
technique(s) ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 Q13541
UniProt登记号 Q13541
运输 wet ice
储存温度 ?20℃
Gene Information human ... EIF4EBP1(1978)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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