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Anti- Notch1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701083
包装型号
规格纯度
价格
4668.88 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti- Notch1 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.

免疫原

A synthetic peptide of human Notch1

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 polyclonal
形式 liquid
species reactivity rat, human, mouse
浓度 1.329 mg/mL
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号 P46531
运输 wet ice
储存温度 ?20℃
Gene Information human ... NOTCH1(4851)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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