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Anti-MLKL antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700092
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-MLKL antibody produced in rabbit
Mlkl
hMLKL
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.

免疫原

Recombinant protein of mouse MLKL

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 53
54
species reactivity rat, mouse, human
浓度 0.68 mg/ml
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
运输 wet ice
储存温度 ?20℃
Gene Information mouse ... MLKL(74568)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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