Anti- CASP1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

免疫原

Recombinant protein of human CASP1.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	all
浓度	2.3 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	P29466
运输	wet ice
储存温度	?20℃
Gene Information	human ... CASP1(834)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable