Anti- B4GALT1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5′ end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 50-215 of human B4GALT1 (NP_001488.2).

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	rat, mouse, human
浓度	1.23 mg/mL
technique(s)	immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000
UniProt登记号	P15291
运输	wet ice
储存温度	?20℃
Gene Information	human ... B4GALT1(2683)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable