半岛bd体育手机客户端 说明
一般描述
Albendazole sulfoxide is a blood-brain barrier main metabolite of anti-parasitic agent albendazole that acts as a antihelminthic. It binds to colchicine binding site of β-tubulin and prevents polymerization. Albendazole sulfoxide exhibits greater affinity to parasitic β-tubulin than to mammalian.
应用
Metabolomics research
生化/生理作用
罗苯达唑是阿苯达唑的关键代谢产物，并作为驱虫药。研究表明，它可能通过使细胞周期停滞在 G2/M 期而诱导人癌细胞 HT-29 凋亡。
基本信息
| 经验(实验)分子式 | C12H15N3O3S |
| 分子量 | 281.33 |
| Beilstein | 677664 |
| MDL编号 | MFCD00797922 |
半岛bd体育手机客户端 性质
| 描述 | Modulation and Signaling |
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | solid |
| 颜色 | white to beige |
| 适用性 | HPTLC |
| 储存温度 | 2-8℃ |
| SMILES string | CCCS(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1 |
| InChI | 1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16) |
| InChI key | VXTGHWHFYNYFFV-UHFFFAOYSA-N |
安全信息
| 象形图 |    |
| 警示用语： | Warning |
| 危险声明 | H317 - H361d - H373 - H410 |
| 预防措施声明 | P202 - P260 - P273 - P280 - P302 + P352 - P308 + P313 |
| 危险分类 | Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
