半岛bd体育手机客户端 说明
应用
Alanine racemase is used to convert L-alanine into D-alanine. Alanine racemase, from Sigma, has been used to isomerize L-[U-14C]alanine to a racemic mixture of L/D- [14C]alanine ?.
生化/生理作用
Alanine racemase is involved in alanine, aspartate and D-alanine metabolism. 3-Fluoro-D-alanine and D-Cycloserine are known to inhibit alanine racemase.? Alanine racemase monomer is composed of two domains, an eight-stranded α/β barrel at the N-terminus and a C-terminal domain. The N-terminus includes residues 1-240, whereas the C-terminal comprises of the β-strand (residues 241-388). One molecule of pyridoxalphosphate (PLP) is present as the cofactor in each subunit.?
单位定义
One unit will convert 1.0 μmole of
外形
Aqueous solution containing 10 mM potassium phosphate
基本信息
酶学委员会(EC)编号 | 5.1.1.1 ( BRENDA | IUBMB ) |
MDL编号 | MFCD03454300 |
NACRES | NA.54 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
生物来源 | Bacillussp. (B. stearothermophilus) |
形式 | buffered aqueous solution |
specific activity | ≥10 IU/mg solid |
分子量 | Mr78 kDa (2 subunits 39 kDa each) |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich