半岛bd体育手机客户端 说明
包装
10 mg in glass bottle
50 mg in poly bottle
生化/生理作用
2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competitive inhibitor of cytochrome P450 1B. It is a synthetic trans-stilbene analog. TMS is an analog of resveratrol and is an anti-cancer agent. TMS is cytotoxic to gefitinib-resistant (G-R) non-small-cell lung cancer (NSCLC) cells. It binds to sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) and promotes apoptosis and autophagy. TMS is also a selective inhibitor of CYP1B1.
基本信息
经验(实验)分子式 | C18H20O4 |
分子量 | 300.35 |
MDL编号 | MFCD03428621 |
PubChem化学物质编号 | 329824983 |
NACRES | NA.79 |
半岛bd体育手机客户端 性质
测定 | ≥98% (HPLC) |
形式 | powder |
technique(s) | HPLC: suitable |
颜色 | white to yellow |
储存温度 | ?20℃ |
SMILES string | COC1=CC(OC)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2 |
InChI | 1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+ |
InChI key | JDBCWSHYEQUBLW-AATRIKPKSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich