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TFF3 human

品牌
Sigma-Aldrich
货号
SRP3169
规格纯度
recombinant, expressed inE. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
价格
4582.93 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
TFF3 human
Intestinal trefoil factor
TFI
Trefoil Factor 3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The trefoil factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract. They are secreted peptides which are protease-resistant. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to be expressed in certain cancers, including colorectal, hepatocellular, and in biliary tumors. Recombinant human TFF3 is a 13.2kDa homodimeric protein consisting of two 59 amino acid chains, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

生化/生理作用

The trefoil factor peptides (TFF1, TFF2 and TFF3) appear to play an important role in intestinal mucosal defense and repair. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.

序列

EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

外形

Lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥98% (HPLC)
≥98% (SDS-PAGE)
形式 lyophilized
效能 1.0-10.0 mg per mL
分子量 13.2 kDa
包装 pkg of 20 μg
technique(s) cell culture | mammalian: suitable
杂质 <0.1 EU/μg endotoxin, tested
颜色 white
UniProt登记号 Q07654
运输 wet ice
储存温度 ?20℃
Gene Information human ... TFF3(7033)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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