3β-(β-D-glucopyranosyloxy)-2β,16α,23,24-tetrahydroxy-O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-olean-12-en-28-oic acid

品牌

Sigma-Aldrich

CAS

58479-68-8

货号

SMB00424

包装型号

规格纯度

≥98% (HPLC)

价格

3697.87 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

58479-68-8
Platycodin D
3β-(β-D-glucopyranosyloxy)-2β,16α,23,24-tetrahydroxy-O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-olean-12-en-28-oic acid
桔梗皂苷D

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Platycodin D (PD) is a triterpenoid saponin found in the root ofPlatycodon grandiflorascalled Platycodonis Radix.

应用

Platycodin D has been used:

to test its anti-inflammatory and inhibitory effect on eosinophilic airway inflammation and T-helper type 2 (Th2) signaling pathways using ovalbumin (OVA)-induced allergic asthma mouse model
to test its anti-obese effects on the activation of brown adipose tissue featuringin vivoandin vitrostudies
to test its efficacy as an adjuvant with infectious bronchitis (IB) vaccine in chicken

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

Platycodin D elicits strong anti-cancer properties and exhibits cytotoxicity against several cancer cell lines of both in vitro and in vivo origin. It exerts anti-inflammatory and protective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by upregulating liver-X receptors α (LXRα) and ATP-binding cassette transporter A1 (ABCA1) signaling pathway. It also possesses protective effects against Cisplatin (CDDP)-induced nephrotoxicity in mice.

基本信息

经验(实验)分子式	C₅₇H₉₂O₂₈
分子量	1225.32
PubChem化学物质编号	329825010
NACRES	NA.25

半岛bd体育手机客户端性质

质量水平	200
测定	≥98% (HPLC)
形式	powder
储存温度	2-8℃
SMILES string	O[C@@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C(CO)(CO)[C@]3([H])CC[C@@]4(C)[C@]5(C)C[C@@H](O)[C@@]6(C(O[C@H]7[C@H](O[C@@H]8O[C@@H](C)[C@H](O[C@H]9[C@H](O)[C@@H](O[C@@H]%10OC[C@@](CO)(O)[C@H]%10O)[C@H](O)CO9)[C@@H](O)[C@H]8O)[C@@H](O)[C@@H](O
InChI	1S/C57H92O28/c1-23-40(81-45-39(72)41(30(64)18-76-45)82-49-43(73)56(75,21-61)22-78-49)36(69)38(71)46(79-23)83-42-33(66)29(63)17-77-48(42)85-50(74)57-12-11-51(2,3)14-27(57)24-7-9-52(4)26-13-28(62)44(84-47-37(70)35(68)34(67)31(16-58)80-47)55(19-59,20-60)25(26)8-10-54(52,6)53(24,5)15-32(57)65/h7,23,25-49,58-73,75H,8-22H2,1-6H3/t23-,25+,26-,27-,28-,29-,30+,31+,32+,33-,34+,35-,36-,37+,38+,39+,40-,41-,42+,43-,44-,45-,46-,47-,48?,49-,52+,53+,54+,56+,57+/m0/s1
InChI key	RJDYKSRQTBCKLC-XTIQGCOGSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P301 + P312 + P330
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable