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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-PRKAR2A, (N-terminal) antibody produced in mouse

Monoclonal Anti-PRKAR2A, (N-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1404240
规格纯度
clone 3C7, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-PRKAR2A, (N-terminal) antibody produced in mouse
PRKAR2
PKR2
MGC3606
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). (provided by RefSeq)

免疫原

PRKAR2A (AAH02763, 1 a.a. ~ 105 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETY

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3C7, monoclonal
形式 buffered aqueous solution
分子量 antigen ~37.55 kDa
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG1κ
NCBI登记号 BC002763
UniProt登记号 P13861
运输 dry ice
储存温度 ?20℃
Gene Information human ... PRKAR2A(5576)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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