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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-APEX1 antibody produced in mouse

Monoclonal Anti-APEX1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403556
规格纯度
clone 3E12, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-APEX1 antibody produced in mouse
HAP1
APEX
APX
APE
APE-1
REF-1
APE1
REF1
APEN
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. (provided by RefSeq)

免疫原

APEX1 (AAH02338, 1 a.a. ~ 318 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3E12, monoclonal
形式 buffered aqueous solution
分子量 antigen ~61.09 kDa
species reactivity human
technique(s) capture ELISA: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
同位素/亚型 IgG2aκ
NCBI登记号 BC002338
UniProt登记号 P27695
运输 dry ice
储存温度 ?20℃
Gene Information human ... APEX1(328)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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