半岛bd体育手机客户端 说明
一般描述
The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon-? (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).
特异性
Antibody recognizes Human CD54 antigen.
免疫原
TNF-activated human umbilical vein endothelial cells
应用
Research Sub Category
Immunoglobulins & Immunology
Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC.
Research Category
Inflammation & Immunology
质量
Evaluated by flow cytometry using human lymphocytes
目标描述
90 kDa (Springer, 1990)
外形
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Protein A purified
储存及稳定性
Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析说明
Control
Human Lymphocytes
法律信息
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.44 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | FITC conjugate |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 6.5B5, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark? |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgG1κ |
| NCBI登记号 | NP_000192 |
| UniProt登记号 | P05362 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
